The University of Washington
Department of Bioengineering
Invites Applications for Tenure Track Position in Synthetic Biology
The 2011 University of Washington iGEM Team won the Grand Prize for their project, “Make It or Break It:Diesel Production and Gluten Destruction, the Synthetic Biology Way!” Congratulations to all!
Article Published: Standard Biological Parts Knowledgebase by Galdzicki, Rodriguez, Chandran, Sauro, and Gennari
March 1, 2011
Standard Biological Parts Knowledgebase
Galdzicki M, Rodriguez C, Chandran D, Sauro HM, Gennari JH (2011) Standard Biological Parts Knowledgebase. PLoS ONE 6(2): e17005. doi:10.1371/journal.pone.0017005
Abstract
We have created the Knowledgebase of Standard Biological Parts (SBPkb) as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org). The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org). SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL), a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate “promoter” parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.
Essential information for synthetic DNA sequences : Nature Biotechnology
Jean Peccoud, J Christopher Anderson,Deepak Chandran,Douglas Densmore,Michal Galdzicki,Matthew W Lux,Cesar A Rodriguez, Guy-Bart Stan & Herbert M Sauro
The Synthetic Biology Data Exchange Group calls for more disclosure of sequence data for synthetic biology papers.
Our first meeting for iGEM 2011 will be on Monday Jan 10th at 4:30pm in HSB K450. iGEM will be introduced for all interested